بررسی قدرت پروکلسی‌تونین سرم در تشخیص پیلونفریت حاد کودکان

Abstract Background: In the absence of specific symptomology in children, the early diagnosis of acute pyelonephritis is a challenge, particularly during infancy. This study was performed to evaluate the diagnostic utility of serum procalcitonin levels in children with acute pyelonephritis.. Methods: Serum procalcitonin was measured with a rapid, semi-quantitative immune-chromatographic test in 56 children who presented with symptoms of UTI a level >0.5 ng/mL was considered abnormally elevated. A DMSA scan was done on all cases and the procalcitonin levels were compared with the DMSA study positive and negative predictive values, (ppv & npv), were determined. Results: The procalcitonin test was positive in 43 of the 49 patients with a positive DMSA scan p.p.v. of the procalcitonin test was 95.3% n.p.v was 38.5%. Conclusion: Procalcitonin test may be utilized as a sensitive marker for early diagnosis of acute pyelonephritis. Keywords: Acute pyelonephritis, Procalcitonin, DMSA.